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Further research has revealed that PNS could inhibit the Wnt/-catenin signaling pathway through downregulating p-GSK3, -catenin, c-Myc and GSK3 to suppress CRC development (Zhang et al., 2021) (Table 2)

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These protective plant compounds are associated with numerous health benefits from lower incidences of heart disease and obesity to maintaining good skin

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Selenium and iodine levels in subjects with Kashin-Beck disease: a meta-analysis

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doi: 10.1007/s42770-020-00327-9, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] Bottery M

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297 The results from the two studies have shown that inhibiting lipid synthesis is possibly able to downregulate anti-inflammatory effects of Treg cells and proinflammatory effects of CD8 + T cells, which should be validated in further studies

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