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Comparison of primary human hepatocytes and hepatoma cell line Hepg2 with regard to their biotransformation properties

39 However, these dosing guidelines are empirical and based on case reports and do not take into account the pharmacokinetics of exogenously administered Lcarnitine

doi: 10.3389/fendo.2024.1338345 Received 14 November 2023 Accepted 22 January 2024 Published 02 February 2024 Volume 15 - 2024 Edited by Corin Badiu, Carol Davila University of Medicine and Pharmacy, Romania Reviewed by Mirjana Doknic, University of Belgrade, Serbia Rita Indirli, University of Milan, Italy Updates Copyright 2024 Dzialach, Sobolewska, Zak, Respondek and Witek

Only when genes and enzymes are linked to chemical transformations of PFAS can we be convinced of what is occurring