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According to Brett, J., & Murnion, B.s 2015 study, Management of benzodiazepine misuse and dependence, this table outlines the various neurological, psychological, and musculoskeletal symptoms associated with benzodiazepine withdrawal symptoms: Understanding the Causes of Benzodiazepine Addiction Common causes of benzodiazepine addiction include prolonged use of prescribed medications leading to physical dependence, self-medication for anxiety or stress, underlying mental health disorders , and a history of substance use disorder

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Studies both in macrophage cell lines and in alveolar and bronchial epithelial cells show that oxidants cause the release of inflammatory mediators (e.g., IL-8, IL-1, and NO) and that these events are associated with increased expression of the genes for these inflammatory mediators and with increased nuclear binding and activation of NF-B (Jimnez et al