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Guggenheim Museum, New York

IGF-1 elevation Growth hormone doesn't directly cause most of its effects

VayneCNguyenT-HRollinJCharuelNPouponAPouplardCet al

Activation of these receptors triggers two complementary processes: it accelerates lipolysis (the breakdown of stored triglycerides into free fatty acids for energy) while simultaneously inhibiting lipogenesis (the conversion of glucose and other substrates into new fat stores)