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Most clinicians diagnose PCOS using the Rotterdam Criteria , which require two of the following three features (2): 1

Wilkinson HN, Roberts ER, Stafford AR, Banyard KL, Matteucci P, Mace KA, et al

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Pike KE, Savage G, Villemagne VL, Ng S, Moss SA, Maruff P, et al

Finding a consistent, stable, and replicable circulating cytokine profile to act as a specific ME/CFS diagnostic has proven difficult to achieve, due to the sensitivity of cytokines to biological mechanisms, and widespread differences in cytokine laboratory methodology [49, 115, 149, 150]