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On one hand, copper deficiency impairs SOD1 activity, compromising antioxidant defenses and leading to oxidative stress accumulation (33)

Flavonoids The class of polyphenols most represented in the Mediterranean diet is that of flavonoids, vegetable pigments which have a basic structure consisting of a skeleton composed of 15 carbon atoms (C-15) arranged in three rings: two benzyl ringscalled A and Band a heterocyclic ringdesignated as C (see Figure 4)

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10 The highest fibre foods are: Not to be confused with pro biotics, prebiotics are food for gut bacteria

The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)