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It disrupts the interaction between FOXO4 and p53, causing senescent cells to undergo apoptosis (programmed cell death) without affecting healthy cells

Beltsos, a double board-certified physician with decades of specialized expertise in women's health, hormone medicine, and medical aesthetics

First, it serves as the primary pathway for ATP generation when oxygen is limited or in cells without mitochondria, such as red blood cells

The level of thymidylate synthase (TS) protein was also high in the heart tissue (100)

NT5C2 germline variants alter thiopurine metabolism and are associated with acquired NT5C2 relapse mutations in childhood acute lymphoblastic leukaemia