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found that targeting cGAS and inhibiting lactylation modifications can promote the transition of microglia from the M1 phenotype to a repair phenotype [110], the addition of lactate has no effect on the expression of A2 astrocytes and only weakens M1 polarization process [57]

We explored this by analysing the expression pattern of Bim and PUMA , the downstream effectors of the Bcl-2 family

The HPV vaccine currently used in the United States, Gardasil 9, can protect against nine of the cancer-causing HPV strains

The only available selective beta-blocker medication is betaxolol (Betoptic, Betoptic S)

Bifidobacterium can also effectively prevent the translocation of bacterial derivatives, such as lipopolysaccharide, to the liver via the portal vein, thereby alleviating hepatic inflammatory responses and endoplasmic reticulum stress [39]