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The study hypothesizes that PT-141 might function by potentially activating dopamine terminals located in the mPOA, but further research is needed to confirm this

Int Ophthalmol Clin 2006 Winter;46(1):133-149

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Histologically, melanomas arising on the external ear are most frequently superficial spreading melanomas (33-46%), followed almost equally by lentigo maligna (19.6%-26%) and nodular (16-22%) types