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Mood and emotional well-being Some early reports and practitioner observations suggest that Dihexas effects on neural connectivity may extend to emotional resilience and mood, possibly through improved prefrontal-limbic circuit function

Constipation is another common issue, reported in 21-25% of retatrutide users and a significant percentage of cagrilintide users

The much larger, headline-grabbing numbers associated with cagrilintide in the press figures in the low-to-mid 20% range come from Phase 3 trials of CagriSema , the combination with semaglutide, and are company-reported topline results, not standalone-cagrilintide data and not the peer-reviewed Phase 2 result cited above

W., Woodhead, J