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Interventions using histone deacetylase inhibitors or strategies that suppress histone lactylation mitigate neuropathy in preclinical models, indicating that histone-modifying pathways may serve as potential biomarkers and therapeutic targets (Zhang J

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Coupling of the first amino acid to SEA PS solid support : The first amino acid (10 equiv) was manually coupled to SEA PS solid support (1 equiv) at rt using HATU (10 equiv)/DIEA (20 equiv) activation in DMF