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10.1016/j.lfs.2019.116592 27

6.3 NAD + -consuming enzyme inhibitors NAD + boosters also include inhibitors of NAD + -consuming enzymes

J Clin Neurosci

Additionally, mRNA expression of iron response element binding protein 2, encodes a master regulator of iron metabolism), and CS (citrate synthase, regulating the mitochondrial fatty acid metabolism) was upregulated in both models, while ACSF2 ((acyl-CoA synthetase family member 2, regulating the mitochondrial fatty acid metabolism) was upregulated only in APPswe/PS1dE9 mice