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The exact cause is unknown, and theres currently no cure, so treatment focuses on symptom relief

For instance, ROS may have played a key role in drug-induced retinopathy (such as the antimalarial drug chloroquine and the antibiotic gentamicin)

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[1] Catalytic mechanism of phosphopentose isomerase The catalytic mechanism of phosphopentose isomerase resembles that of phosphohexose isomerase (EC 5.3.1.9), a glycolytic enzyme