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The first, PER2LUC, is a transgenic model in which the Per2 gene promoter drives the expression of a firefly luciferase enzyme fused to the PER2 protein

Prior to this report, there were no published reports of any pharmacologically and chemically attractive, selective small molecule activator probes to dissect the molecular mechanisms the apoptotic arm of the UPR activation, even at the phenotypic cell death level

L., Wong, J., Northcott, M

Mesenchymal stem cells Also known as stromal cells , these stem cells are present in many tissues such as bone, cartilage and fat

Statistical analysis was performed using two-tailed Students t -test ( b ), two-tailed Mann-Whitney test ( g , h ), and one-way ANOVA ( d )