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These antibodies likely bind myelin or other neural antigens and, together with complement, mediate myelin destruction

10.1016/j.pestbp.2017.08.008 96 TaylorC.CrosbyI.YipV.MaguireP.PirmohamedM.TurnerR

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CGMP refers to the Current Good Manufacturing Practice regulations enforced by the FDA

To examine the relationship between ROS and caspase-3-mediated lipid scrambling during NET formation, we employed DPI and apocynin (NADPH oxidase inhibitors), as well as NA-11 (an inhibitor of NOX2-dependent oxidative burst in neutrophils by activating the glycolytic enzyme phosphofructokinase-1 liver type, PFKL) in PMA-induced NETs 36