glutamine and glutathione synthesis Metabolic orchestration driven by GGCT: diverting to biosynthesis while enhancing glucose anaplerosis for tumor proliferation The synthesis of glutathione (GSH),

Additionally, evidence suggests transcription factors regulate SLC7A11 expression to modulate ferroptosis

Interestingly, nitric oxide inhibits mitochondrial respiration by reacting with either the reduced or the oxidized binuclear site of cytochrome c oxidase, leading to ATP depletion

Of note, intra-abdominal hypertension is quite frequent in critically ill patients and the cause of multiorgan dysfunction (Vukojevic et al., 2018

We synthesize animal, cellular, and human (bulk/single-cell) data to define cell- and stage-specific roles of GLS1 in atherosclerosis and to outline translational opportunities

Enhances overall nutrient balance and absorption