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Nevertheless, the levels and balance of total and reduced glutathione in lung tissue of ApoE -/- mice at 24 h after last exposure were not affected, indicating that the pulmonary exposure did not cause oxidative stress in the lungs (or it was too late to investigate this end-point)

That's why it's important to let your doctor know if you have any of the following conditions before you're prescribed hydroxocobalamin: If you've had an allergic reaction to hydroxocobalamin or any other medicines in the past If you've been diagnosed with low levels of potassium If you have an irregular or fast heartbeat Once you've started taking hydroxocobalamin, you may have some side effects such as pain, swelling, or itchy skin at the point where the syringe was injected

and down-regulation of enzyme synthesis (19, 30, 34, 52)

This leads to inflammation in many ways

The Merck manual