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[48] Vegan advocacy organizations, among others, recommend that every vegan consume B 12 from either fortified foods or supplements

Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA