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Appearance: Light or dark patches, sometimes reddish or brownish

We then focused on mTOR because this molecule is a key regulatory factor in tumor development, and inhibiting mTOR is considered promising method in tumor treatment [25, 26]

Commonly used measures, such as deficits in social interaction or repetitive behaviors, are present in many neuropsychiatric disorders, which limits the construct and face validity of the models used [102, 133]