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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

[DOI] [PubMed] [Google Scholar] 103.Stnder S., Schmelz M., Metze D., Luger T., Rukwied R

Finally, a network meta-analysis incorporating data from 50 randomized placebo-controlled trials involving approximately 20,000 AD patients demonstrated that the administration of melatonin (3 mg/day) over a period of 6 to 12 months was associated with improved cognitive function [226]