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The preclinical data showing enhanced tendon healing, ligament repair, and injury recovery is genuinely compelling, and ongoing research may eventually establish clear clinical protocols

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In some embodiments, dyes that are compatible with the otic compositions described herein include Evans blue (e.g., 0.5% of the total weight of an otic formulation), Methylene blue (e.g., 1% of the total weight of an otic formulation), Isosulfan blue (e.g., 1% of the total weight of an otic formulation), Trypan blue (e.g., 0.15% of the total weight of an otic formulation), and/or indocyanine green (e.g., 25mg/vial)

Injection site irritation, headache, nausea, fatigue, and dizziness are among the most commonly reported reactions