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Some investigators have examined both peptides concurrently in tissue repair models, noting that their non-overlapping pathways may produce complementary downstream effects on vascularization and extracellular matrix remodeling

doi: 10.1080/07315724.1999.10718861

For example, the review mentioned one study suggesting creatine may increase manic or hypomanic episodes in people with bipolar disorder and another linking just a week of 25 grams (g) daily supplements to increased nervousness and aggression in 2 out of 10 study participants

The case definition for autistic disorder was not standardised until 1980 when it was included in the DSM-III

In comparison, researchers who administer peptide injections will receive their peptides in the form of lyophilized powder, which must be reconstituted with a sterile solvent like bacteriostatic water