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Reta is patented by Eli Lilly and currently in third-stage clinical trials likely on the way to becoming an approved FDA drug in late 2027 or early 2028

Curr Issues Mol Biol 46:92459254

Homozygosity for mutant NF1 alleles has not been reported, probably because it is a lethal condition

Sci Rep 13:5650 Vilas-Boas JA, Cardoso SJ, Senra MVX, Rico A, Dias RJP (2020) Ciliates as model organisms for the ecotoxicological risk assessment of heavy metals: A meta-analysis

The reason for this is that the CMOS sensor on the 10D occupies about 63% of the normal 35mm linear film dimensions rather than covering the entire conventional 35mm film space