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The doses are not interchangeable, and a milligram of retatrutide is not equivalent to a milligram of tirzepatide, because the receptor activation profiles are completely different

1.Biosynthesis of Eicosanoids Eicosanoids are synthesized through the enzymatic oxidation of polyunsaturated fatty acids (PUFAs), primarily arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA)