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Bellis, G

observed that a regimen inclusive of vitamin E led to augmented sperm concentration and diminished DNA damage in infertile patients, although the motility and morphology remained largely unchanged [78]

People with chronic kidney disease have a reduced ability to clear extra fluid and certain solutes including vitamin C metabolites making high or frequent IV dosing a risk for edema and kidney injury

Reactive oxygen species have been determined to be critical inducers of various forms of cell death, which are collectively termed oxidative cell death [5]