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Ethics declarations Ethics approval and consent to participate This systematic review, representing a partial execution of the PhD student project entitled"Effects of plasma rich in growth factors in human immature testicular tissue culture,"received ethical clearance from the Research Ethics Committees of Tabriz University of Medical Sciences on September 4, 2023 (Approval ID: IR.TBZMED.REC.1402.410)

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At astrocyte stage, there is a negative regulation of terms reflecting a reduction in the recruitment of protein complexes to chromatin (regulation of protein localization to chromatin), recognition of acetylated histones typically associated with open chromatin and active transcription (lysine acetylated histone binding, acetylation-dependent protein binding), and fine-tuning transcriptional repression (SUMO ligase complex), potentially leading to impaired gene activation and aberrant chromatin states

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Prada-Ramallal G, Takkouche B, Figueiras A