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If fatigue persists or worsens over time, checking B12 levels, thyroid function, and other nutritional markers is warranted

This is especially common in older adults, who often consult multiple organ-specific specialistsneurologists, gastroenterologists, endocrinologistswithout cross-communication between them

10.1203/PDR.0b013e318123f719 83

However, the drug is not without drawbacks

This siRNA-induced silencing complex degrades the passenger strand of siRNA and integrates it into the guide RNA, triggering sequence- specific cleavage of the mRNA