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It's the lack of sleep, its the electronics in the evening before you go to bed, its the absence of exercise, its the medications, and its the large amount of processed foods present in our diet, he says

Organotypic hippocampal slice cultures maintain a more intact perforant path and therefore represent a more intact environment

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While DBAN is probably not mutagenic, it effectively alkylates DNA in vitro which may explain how it breaks DNA and elevates sister chromatid exchange in yeast and mammalian cells 9,10,11