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I., Fromholt, S

Synergistic effects on blood glucose levels were reported with TQ and GBC [306]

Nov 2022;32(11):2493-2504

The working efficiency of GPX4 depends entirely on whether there is selenium cysteine on its active site and whether there is enough GSH in the cell

Since these residues are buried within the IMiD-binding site, we hypothesized that they might reflect differences in the binding mode of the dHTC1 spirosuccinimide compared to traditional glutarimide-based CRBN ligands