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6:6479 doi: 10.1038/ncomms7479 (2015)

The relationship between common pathogenic variants and the phenotypic syndromes of mitochondrial diseases is summarized in Table 2

The cough suppressant dextromethorphan may cause false-positive PCP 1,2,4 and opioid levels due to its metabolites similarity to the opioid agonist levorphanol

The main risks are skin irritation with high concentrations and the contamination concerns associated with poorly sourced or improperly prepared formulations