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In healthy skin, melanin functions to protect against Ultraviolet (UV) radiation by preventing direct DNA damage by absorbing (UV-A/B) thus preventing subsequent ROS-mediated genotoxicity 1315

The stunted phe- notype of mutants such as cat2 and derived lines, which accumulate GSSG when grown from seed in air, may be related to such thiol regulation of plant growth, as could the effects of GSH on the regeneration efciency of somatic embryos (Belmonte et al

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Finally, it has been shown that persistent DNA damage signaling contributes to the secretion of the SASP factors, highlighting the role of oxidants in senescent cells and their impact on the organism (Rodier et al., 2009)

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