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MiT/TFE factors control ER-phagy via transcriptional regulation of FAM134B

This suggests that SIRT1 agonists (e.g., resveratrol) could represent a novel therapeutic strategy for cancer by modulating the tumor microenvironment to suppress metastasis and angiogenesis

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In addition, while the antibody can be from essentially any mammalian species, to reduce immunogenicity, it is desirable to use an antibody that is of the species in which the antibody and/or immunoconjugate is to be used