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Description

IR-Tac Pharmacokinetics The median (IQR) total daily doses of IR-Tac on days 1, 7, and 14 were 16.5 mg (14.018.75), 10 mg (7.7512), and 8 mg (5.7510.5), respectively (Table 3)

The observed treatment effects align with the ones proposed by the C3G Trial Endpoints Workgroup (Nester, C

The Keap1Nrf2 [Kelch-like ECH-associated protein 1nuclear factor (erythroid-derived 2)-like 2] system is one of the most critical cytoprotective mechanisms acquired in vertebrates over the course of evolution (Morita and Motohashi, 2011)