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GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) GHK-Cu is a naturally occurring copper complex first identified in human plasma

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To explore the antiviral synergy of these two drugs in vivo and to recapitulate the scenario in which most patients with COVID-19 will be treated after the onset of disease, we gave SARS-CoV-2-infected hamsters oral clofazimine and intraperitoneal remdesivir together: the first doses were given 24 h after virus challenge