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Beck and colleagues reported in 2014 that the 117-patient proof-of-concept study found ipamorelin well tolerated but did not reach statistical significance on its primary composite gastrointestinal endpoint at the studied dose

Cigarette smoke can reduce the expression of Frizzled receptor 4 (FZD4) in alveolar epithelial cells and enhance the phosphorylation of -catenin, inhibiting epithelial proliferation and alveolar repair mediated by the classic Wnt signalling pathway

Right ventricular pressures were measured with a high-fidelity pressure catheter inserted in the right ventricle via cannulation of the right jugular vein, to monitor the development of pulmonary hypertension

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ACS Appl Mater Interfaces 12(40):4450844522 Lin S et al (2020) Antioxidative and angiogenesis-promoting effects of tetrahedral framework nucleic acids in diabetic wound healing with activation of the Akt/Nrf2/HO-1 pathway