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Thus, in this study our initial goal was to identify LOX-metabolites (particularly 4-OXO-DHA) in rats administered DHA by oral gavage twice weekly until termination of the bioassay ( cf

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However, the effect of DEG treatment on these modifications differed over time, with 24 h DEG treatment required for substantive changes on lipoylation, although PDHc-E2 glutarylation was observed at 6 h (Extended Data Fig