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F.HassanA.et al (2016)

September 9, 2025

The compound simultaneously elevates SAM concentrations, supporting healthy epigenetic regulation and polyamine synthesis

Consistent with these findings, other researchers discovered that RSL3 can downregulate the levels of HK2, phosphofructokinase (PFKP) and PKM2, which makes glycolysis dysfunctional, thus enhancing the sensitivity of tumors to ferroptosis [34]