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elegans insulin signaling pathway include ILPs (Hua et al

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Anti-LDL-monoclonal antibody had a protective effect against atherosclerosis in LDL receptor knockout mice [19]

More high-throughput screens have been used to identify new classes of compounds, such as the glycerol ethers niphatenones isolated from the sponge Niphates digitalis, which are proposed to covalently bind the AF1 and may serve as lead compounds for further drug development 180