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Purging: When you introduce an active like azelaic acid that affects cell turnover, a 'purging' phase can occur, where underlying microcomedones come to the surface

Likewise, in an aSyn mouse model of PD a high fat diet led to an accelerated development of locomotor phenotype and earlier onset of neurodegeneration (123)

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We next explored whether the NRF2 system in SCLC is capable of responding to inhibition of KEAP1, the E3 ligase responsible for regulating NRF2 protein levels