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10.1038/s41416-021-01566-9 Br J Cancer

3.3 Oxidative stress Oxidative stress generally refers to a state of imbalance between oxidation and antioxidant defense system (126)

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While initially activated by their pro-inflammatory microenvironment, at a certain stage, fibroblasts acquire an epigenetically imprinted aggressive phenotype switching from responders to drivers, and hence switching the disease from acute to chronic ( in vivo

For GTTs, animals were fasted for 4 h and a baseline blood glucose measurement was made prior to administering a 2 mg/kg i.p