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Because it blocks the production of folate, Alimta is considered an antifolate antimetabolite

doi: 10.1016/j.jgr.2015.04.009 320

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The hypoxic microenvironment promotes angiogenesis within fibroid tissue, yet the resulting blood vessels exhibit abnormally thin walls

158,159,160 Recent research shows that hepatocytes release cholesterol and C-X-C motif chemokine ligand 1 (CXCL1), drawing neutrophils from the bone marrow to the injured liver, where they subsequently secrete HGF to enhance hepatocyte proliferation and support liver regeneration