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RGS proteins maintain robustness of GPCR-GIRK coupling by selective stimulation of the G protein subunit Go

RGC degeneration is a common cause of glaucoma and optic neuropathy, which is the main cause of irreversible blindness and visual impairment (Ju et al., 2023)

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Since we previously found that ser/gly rewired tumors produce and secrete high levels of pathway metabolites into the circulation, we hypothesized that metabolomic analysis of blood plasma samples from patients with NSCLC could give valuable insight into ser/gly metabolic rewiring in tumor cells in response to RT [24]