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Description

(2014) 9:e100352

216 National Institute on Aging (2024)

Esteras, N

GSH is required for proper actin-based motility and cell-to-cell spread of R

Compounds spanning 100-fold IC50 values for NNMT inhibition were selected on the basis of positional substitutions around the N-methylated quinolinium scaffold to obtain an estimate of drug-like oral absorption/bioavailability properties and guide the choice of inhibitors for in vitro and in vivo phenotypic studies