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Brain-focused conclusions require an appropriate combination of neural tissue, cerebrospinal fluid, imaging, or mechanistic models

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Key properties: Stimulates GH release from the pituitary (not the hypothalamus) Does not significantly raise cortisol or prolactin Short half-life (~2 hours) produces a sharp, pulsatile GH release Does not block somatostatin (the hormone that inhibits GH release) Selective for GH minimal effect on other hormones The selectivity is what makes ipamorelin the preferred GHRP for most protocols

High chemokine receptor CXCR4 level in triple negative breast cancer specimens predicts poor clinical outcome