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Sodium 2-mercaptoethane sulfonate (Mesna) has traditionally been employed in clinical practice to counter cyclophosphamide-induced cystitis in humans

Artesunate inhibited the Notch signaling pathway, decreased Jagged1, NICD, and Hes-1 protein expression, reduced TGF-induced -smooth muscle actin (-SMA) and collagen content in fibroblasts, and inhibited the differentiation of fibroblasts into myofibroblasts (Liu et al., 2017)

found that SeNPs stabilized with chitosan (CS) of different molecular weights exhibited significantly reduced cytotoxicity in BABLC-3T3 and Caco-2 cells (53)

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Their role in neuroprotection is primarily attributed to their ability to mitigate oxidative stress, reduce neuroinflammation, modulate neurotransmitter activity, and enhance neurogenesis (Butterfield and Halliwell 2019)