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doi:10.1016/j.forsciint.2010.02.021

Lipid peroxidation increases ROS generation and damages cell membranes, activating a series of pro-apoptotic signaling molecules (e.g., caspase-3, p53), which lead to muscle cell apoptosis

[DOI] [PMC free article] [PubMed] [Google Scholar] Emerich DF, Dean RL, Bartus RT