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For endurance athletes specifically, Centner, Jerger, and Knig published a randomized controlled trial in Nutrients (2023) examining recreationally active men who combined 12 weeks of concurrent training60 minutes of moderate-intensity running plus 15 minutes of dynamic resistance workwith daily SCP supplementation

Additionally, avoiding caffeine and certain pain medications around the time of supplementation can help maximize its effects

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Abbreviations AOPP: Advanced oxidation protein product BM: Bacopa monnieri CN: Control CYP: Cypermethrin CAT: Catalase DCF: 2,7-Dihydrodichlorofluorescein diacetate DAPI: Dihydrochloride dye ELISA: Enzyme-linked immunosorbent assay GSH: Glutathione GST: Glutathione- S transferase GR: Glutathione reductase GPx: Glutathione peroxidase H 2 O 2 : Hydrogen peroxide LPO: Lipid peroxidation MDA: Malondialdehyde NO: Nitric oxide NADPH: Nicotinamide adenine dinucleotide phosphate 3PBA-3: Phosphobenzoic acid ROS: Reactive oxygen species SOD: Superoxide dismutase T 3 : Tri-iodothyronine T 4 : Thyroxine TSH: Thyroid stimulating hormone THR -1: Thyroid hormone receptor beta 1 TSHr: Thyroid stimulating hormone receptor References Al-Amoudi WM (2018) Toxic effects of Lambda-cyhalothrin on the rat thyroid: involvement of oxidative stress and ameliorative effect of ginger extract

Without adequate nitric oxide, blood vessels become stiffer, resistance increases, and the heart has to work harder to push blood through the system