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This mechanism establishes hADSC-Exos as a viable cell-free regenerative therapy for POF, offering benefits such as low immunogenicity and enhanced safety compared to direct stem cell transplantation (Huang et al

The -catenin-TCF4 complex subsequently activates target genes such as Ccnd1 and initiates the G1-to-S phase transition

Wang Q, Bin C, Xue Q, Gao Q, Huang A, Wang K, Tang N

Chondrocyte-like cells (CLCs) The cells found in the degenerating NP are similar, but not identical, to articular chondrocytes and are therefore termed chondrocyte-like cells (CLCs) [27]

Here is a study where they looked at the change in uric acid excretion from an alkaline diet