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Crucially, the structural similarity between l- and d-lactate suggests a potential for crosstalk and competition

Methods Mol Med 2005

W., Verduzco, D., Schramm, K

In this respect, enhancement of the antimycobacterial activity of macrophages that are manipulated or suppressed by MAC infection and modulation of excessive inflammation are promising strategies for the treatment of MAC infection

This slight increase then leads to an increase in inflammatory cytokines (TNF-alpha, IL-1 beta) in macrophages[ref] Endoplasmic Reticulum (ER) stress, protein misfolding: The endoplasmic reticulum (ER) is an organelle in cells where newly synthesized proteins are folded, lipids are synthesized, and calcium is stored