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doi: 10.1074/jbc.M411379200 14 ShimadaSYanoOInoueHKuramotoEFukudaTYamamotoHet al

Adv Nutr (Bethesda Md)

Interestingly, bortezomib, a potent proteasome inhibitor known to increase microtubule polymerization in neuronal cell line (Poruchynsky et al., 2008), also induced excessive microtubule polymerization in the cell bodies of DRG neurons by increasing hyper-stable delta 2 tubulin (D2) (Pero et al., 2021)